The MUSC Theses and Dissertations collection brings the work of MUSC students to a broader audience. Publishing dissertations in an open access format such as MEDICA@MUSC ensures that student research is not limited to a local audience.

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Theses/Dissertations from 2026

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Building a Precision Medicine Framework for Lupus Nephritis: From Spatial N-Glycan Architecture to Non-Invasive Urinary Biomarkers, Aaron O. Angerstein

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Triazine Thiols Decrease Apolipoprotein B Secretion from Hepatocytes Through Inhibition of Human Carboxylesterase 1, Josef Blaszkiewicz

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Navigating Medicare: A Mixed-Methods Study on Enrollment Literacy and Plan Selection Challenges among First-Time Black Beneficiaries in Southeast Queens, New York, Wiljanda M. Boatwright

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From Gene to Phenotype: Deciphering Cardiac Development and Disease, Kathryn M. Byerly

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Clostridioides difficile Toxins Trigger a Macrophage-ILC3 Axis that Drives IL-22 and MUC13 Induction, Erin C. Chard

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Chimeric Antigen Receptor-Induced Inflammatory Reprogramming of Human Regulatory T Cells, Russell W. Cochrane

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Fentanyl Mediated Distortions of Phasic Dopamine Release Dynamics Encoding Natural Reward and Aversive Processing in the Mammalian Mesolimbic Circuit, Oliver P. Culver IV

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The Staying Power of Leadership: Organizational Support Factors Influencing Leadership Longevity in Healthcare, Marlena Davis

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The Role of BRD4 in the DNA Damage Response of Cancer, Julie A. Disharoon

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Rethinking Performance Measurement in Healthcare: Leadership Perspectives on Value, Burden, and Trade-offs, Sherrie Dorow

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Build, Buy, or Remain Independent: A Transaction Cost Economics Analysis of Hospital Governance Strategies in Florida Acute Care Hospitals (2016–2022), Meeta Gandhi

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Analyzing Variations in 48-Hour Mortality Rates Following Hospital Admission for Trauma Injuries Across Urban and Rural Hospitals, Kimberly Gilbert Henderson

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Circuit and Synaptic Mechanisms of Methamphetamine Induced Cognitive Deficits During Abstinence: Roles of the Perirhinal-Prefrontal Pathway and the Nucleus Reuniens, Sarah Goldsmith

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An MHC Class II-Targeted Cancer Immunotherapy for the Treatment of Pediatric Acute Myeloid Leukemia, Lena R. Golick

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Facilitators and Barriers to Mobile Health Unit Implementation: A Qualitative-Dominant Mixed Methods Study Exploring Staff Perspectives and Service Outreach, Kelsey Hardin

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Psychological Stress and Aortopathy, Heather Holman

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Determining KRAS-Mutant Specific Mechanisms of Daraxonrasib Resistance in PDAC, Grayson Johnson

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Bayesian Hierarchical Model to Determine if Dichotomization is Justified with Extensions to Tree-Based Models, Everette Keller

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Mapping the PDAC Tumor Microenvironment: Glycomic, Proteomic, and Immune Signatures from Premalignancy to Metastatic Disease, Caroline Kittrell

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Young Adult Oncologic Surgical Prehabilitation: Exploring AYA Surgical Oncology Patient and Surgeon Perspectives on Ideal Program Design, Implementation Barriers, and Solutions for Change, Emily L. Kobus

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Examining Hospital Admissions Among Patients (0-21 years) with Autism Spectrum Disorder: A Quantitative Analysis, Tuan Le

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The Burden of Prior Authorizations in Bleeding Disorder Specialty Drugs, Lisa Littner

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Effects of a Major Disruption on Mental Health of Pregnant Women in South Carolina, Lizmarie Maldonado

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Defining the Role of HNF1B in the Transition of the Endoderm to a Hepatic Fate, Carla Martinez Morant

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Prior Mild Cognitive Impairment Among Medicare Beneficiaries With Alzheimer’s Disease: Neuropsychiatric Symptom Burden and Associated Healthcare Costs, Helen Matheny