The MUSC Theses and Dissertations collection brings the work of MUSC students to a broader audience. Publishing dissertations in an open access format such as MEDICA@MUSC ensures that student research is not limited to a local audience.

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Theses/Dissertations from 2026

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Building a Precision Medicine Framework for Lupus Nephritis: From Spatial N-Glycan Architecture to Non-Invasive Urinary Biomarkers, Aaron O. Angerstein

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Navigating Medicare: A Mixed-Methods Study on Enrollment Literacy and Plan Selection Challenges among First-Time Black Beneficiaries in Southeast Queens, New York, Wiljanda M. Boatwright

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From Gene to Phenotype: Deciphering Cardiac Development and Disease, Kathryn M. Byerly

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Clostridioides difficile Toxins Trigger a Macrophage-ILC3 Axis that Drives IL-22 and MUC13 Induction, Erin C. Chard

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Chimeric Antigen Receptor-Induced Inflammatory Reprogramming of Human Regulatory T Cells, Russell W. Cochrane

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The Staying Power of Leadership: Organizational Support Factors Influencing Leadership Longevity in Healthcare, Marlena Davis

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Rethinking Performance Measurement in Healthcare: Leadership Perspectives on Value, Burden, and Trade-offs, Sherrie Dorow

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Analyzing Variations in 48-Hour Mortality Rates Following Hospital Admission for Trauma Injuries Across Urban and Rural Hospitals, Kimberly Gilbert Henderson

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Circuit and Synaptic Mechanisms of Methamphetamine Induced Cognitive Deficits During Abstinence: Roles of the Perirhinal-Prefrontal Pathway and the Nucleus Reuniens, Sarah Goldsmith

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An MHC Class II-Targeted Cancer Immunotherapy for the Treatment of Pediatric Acute Myeloid Leukemia, Lena R. Golick

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Facilitators and Barriers to Mobile Health Unit Implementation: A Qualitative-Dominant Mixed Methods Study Exploring Staff Perspectives and Service Outreach, Kelsey Hardin

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Determining KRAS-Mutant Specific Mechanisms of Daraxonrasib Resistance in PDAC, Grayson Johnson

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Examining Hospital Admissions Among Patients (0-21 years) with Autism Spectrum Disorder: A Quantitative Analysis, Tuan Le

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The Burden of Prior Authorizations in Bleeding Disorder Specialty Drugs, Lisa Littner

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Prior Mild Cognitive Impairment Among Medicare Beneficiaries With Alzheimer’s Disease: Neuropsychiatric Symptom Burden and Associated Healthcare Costs, Helen Matheny

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Quantifying Provider Relief Fund Allocation Trends: A Descriptive Analysis of Rural and Urban Hospitals, 2014-2023, Wendell C. McClurg

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The Impact of the Different VDAC Isoforms on HBV Replication and HBx Localization, Cody McUmber

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Strategic Planning Time Horizons and Hospital Performance Outcomes, David Meyer

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Redesigning Outpatient Chemotherapy Scheduling: A Management Approach to Site-Integrated Operations, Dominick J. Morrone

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Models, Phenotypes, and Genomics: Translational Insights into the Biology of Ehlers-Danlos Syndromes, Taylor Nelson

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Stress Mediated Changes in the Mouse Prefrontal Cortex, Krysten P. OHara

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Geographic Patterns of Pediatric Health and Opportunity: An Analysis of Social Vulnerability, Community Context, and Health Outcomes in South Carolina, Sarah Piwinski

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Patient-Reported Unmet Needs in Young Adult Cancer Care: A Needs Assessment Study, Disha Sawhney

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Quantitative analysis of emergency department holding times in a five-hospital market in an academic health system, Jeffrey Schecter

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Insights into the Role of SOX6 in the Developing Heart, Hannah Tarolli