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MUSC Theses and Dissertations

The MUSC Theses and Dissertations collection brings the work of MUSC students to a broader audience. Publishing dissertations in an open access format such as MEDICA@MUSC ensures that student research is not limited to a local audience.

Theses/Dissertations from 2025 2025

Mitigating Self-Inflicted Mortality Among Senior Veterans Aged 55 and Older with Chronic Conditions: An Exploration of an Innovative Positive-Sum Model Framework Leveraging Chronic Condition Special Needs Plans for Evidence-Based, Multidisciplinary Coordinated Care, Roger W. Blackwell

We Are All Made of Star-Stuff: Targeting Astrocytic Calcium to Prevent Alcohol-Induced Changes in Orbitofrontal Cortex Excitability, Synaptic Dynamics, and Behavior, Abigail Blasczyk

OB/GYN Physician Perspectives on Maintenance of Certification (MOC), Brent Bost

Global ERK/MAPK Activation Determines Oncogenic Fitness in KRAS-Mutant Pancreatic Ductal Adenocarcinoma, Rachel A. Burge

Addressing Generalization Challenges in Clinical Section Identification: Contextual Learning and Large Language Model Approaches, Kexin Chen

Engineering CXCR2-Ligand-Based Fusion Proteins to Modulate Myeloid Cell Trafficking in Pancreatic Cancer, Benjamin N. Christopher

Mouse Model of Post-Traumatic Stress Disorder Demonstrates Negative Alterations of Cardiac Homeostasis, Alexa M. Corker

Bereavement Needs of Parent-Child Dyads Following Sibling Death, Shannon V. D'Alton

Bioelectrically Guided Cancer Therapy: Advancing Toward Clinical Translation, Davide A. Delisi

A Theoretical Model of Clinical Documentation Burden: Exploratory Factor Analysis Investigating Usability, Effort, and Perceived Burden Among Healthcare Providers, Rhiannon Doherty

The Role of Myosin 5b in Intestinal Health and Disease: From Microvilli Assembly to Colorectal Cancer Progression, Sarah Aline Dooley

Molecular Pathology of the Breast Microenvironment Contributing to Risk and Outcome in Breast Cancer Disparities Using Multimodal, Multiplexed Mass Spectrometry Imaging, Jaclyn B. Dunne

The Impact of Diabetes on Neurovascular Integrity: A Special Focus on Pericytes and Endothelin-1, Mia Edgerton

The Impact of Diet-Induced Obesity on Cerebrovasculature Structure and Function, Riley M. Feagle

PCBP1 as a Tumor Suppressor: Enhancing cGAS-STING-Mediated Innate Immunity in Breast Cancer, Cécile H. Fréreux

Risk Management Practices in the Healthcare Supply Chain: A Cross-Sectional Survey of Professionals in Saudi Arabia, Maha Ghamedi

Rural and Urban Disparities in Access to GLP-1 Agonists for Patients with Obesity, Christine J. Hackler-Moorman

Incivility Experienced by Males in Nursing Education, Christopher S. Hale

Quantifying Trends in Hospital Administrative Costs: Examining Urban-Rural Disparities, Barriers, and Opportunities for Cost Reduction in Healthcare, Lauree Handlon

An Investigation into Filopodia-mediated Cellular Entry and Diversification of Payload Capacity of a Cell-penetrating Peptide System for Expanded Gene Therapy Capabilities, Charles E. Holjencin

From Non-invasive to Metastatic Breast Cancer: Pathological Variation in Collagen Signatures within the Extracellular Microenvironment, Taylor S. Hulahan

Oncology Perceptions and Motivations Toward Adopting Artificial Intelligence, Hannah Hylla

The Incidence of Hospital-Acquired Pressure Injuries in the Setting of the Changing Nursing Workforce Throughout the COVID-19 Pandemic, Jacqueline H. Jacobs

From Dysbiosis to Dysfunction: Investigating the Effects of Chronic Cocaine Use on Oral Microbial Shifts and Neuropathogenesis, Douglas E. Johnson

Palmitic Acid-Rich Diet Induced Cerebrovascular Tau Pathology Contributes to the Development and Progression of Cognitive Impairment, Eda Karakaya