Date of Award
Summer 8-12-2024
Embargo Period
8-12-2026
Document Type
Dissertation
Degree Name
Doctor of Philosophy (PhD) in Health & Rehabilitation Science
Department
Health Sciences and Research
College
College of Health Professions
First Advisor
Heather Bonilha
Second Advisor
Dorothea Jenkins
Third Advisor
Janina Wilmskoetter
Fourth Advisor
Christina Pelatti
Abstract
This dissertation investigates innovative approaches to improve feeding and swallowing outcomes in infants, particularly those born prematurely or with brain injury. It focuses on understanding the neural networks involved in sucking and swallowing by utilizing diffusion kurtosis imaging (DKI), a more sensitive neuroimaging technique than traditional MRI, and the BaByVFSSImP, a standardized tool for assessing swallow function. Additionally, the research explores the use of transcutaneous auricular vagus nerve stimulation (taVNS) as a neuromodulation technique to enhance oral feeding skills. The study found no adverse effects from taVNS on airway protection or swallowing physiology. Furthermore, there were some possible associations between specific white matter tracts and components of sucking and swallowing identified. Although these findings are preliminary and should be interpreted with caution. Larger studies are needed to confirm these results and to further explore the neurophysiological underpinnings of infant feeding and swallowing skills. The work provides a foundation for larger, future studies investigating the role of white matter tracts in infant feeding and swallowing.
Recommended Citation
McGhee, Heather, "Neural Control of Swallowing in Infants: White Matter Tracts Associated with Swallow Function" (2024). MUSC Theses and Dissertations. 954.
https://medica-musc.researchcommons.org/theses/954
Rights
Copyright is held by the author. All rights reserved.