Date of Award

Fall 11-16-2023

Embargo Period

12-11-2025

Document Type

Dissertation - MUSC Only

Degree Name

Doctor of Philosophy (PhD) in Health & Rehabilitation Science

Department

Health Sciences and Research

College

College of Health Professions

First Advisor

Aiko Thompson

Second Advisor

Thomas Sinkjær

Third Advisor

Mark Bowden

Fourth Advisor

Daniel Brinton

Abstract

Propulsive force generation by ankle plantarflexors is important for human locomotion. The production of muscle force involves the coordination of inputs from the tripartite system of locomotion: the central pattern generator-like network, supraspinal descending centers, and peripheral sensory afferents acting on motoneurons. Previous work suggests that during stance phase, sensory afferents contribute significantly to generating and reinforcing plantarflexor activity. Therefore, this project includes three separate studies which aim to investigate muscle afferent contributions to plantarflexor activity towards generating propulsive force during walking at various speeds, additional weight loading, and with restricted knee joint motion. To do this, indirect approximations of each muscle afferents’ firing was examined using ankle joint rotation and ground reaction forces during and prior to peak propulsive force to examine the length- and velocity-sensitive afferents (Ia and II) and load-sensitive afferents (Ib), respectively. In all studies, speed was a factor for each study design as a way of encouraging additional propulsion. Across all studies, as walking speed increased, ankle joint rotation generally decreased its amount and maintained its rate of rotation during mid-late stance. Conversely, ground reaction forces increased in both amount and rate during the same phase. Taken together, these findings may suggest a significant role of the load sensitive Ib pathway in the generation and/or enhancement of plantarflexor activity across various submaximal speeds and during a variety of locomotor tasks. The functional implications of these studies could suggest that enhanced loading of the plantarflexors may be an important strategy for rehabilitation protocols.

Rights

Copyright is held by Bridgette A. P. Damewood. All rights reserved.

Available for download on Thursday, December 11, 2025

Share

COinS