Date of Award
1988
Document Type
Dissertation
Degree Name
Doctor of Philosophy (PhD)
Department
Anatomy
College
College of Graduate Studies
First Advisor
Richard M. Dom
Second Advisor
Sam Spicer
Third Advisor
Robert P. Thompson
Fourth Advisor
Bradley Schulte
Abstract
The neural retina is a structure that develops from a simple neuroepithelium into a complex neural organ. The histochemistry of this structure has been studied for many years by scientists using various techniques. In this study, lectin histochemistry, immunohistochemistry and experimental manipulations of retinal cell types have been used in an attempt to clarify the distribution of saccharide moieties in glycoconjugates during retinal development in the rat, the rabbit and the chick. With these methods of investigation we have demonstrated that glycoconjugate patterns vary during development and have also demonstrated the presence of several interesting glycan moieties. The distribution of these molecules in the different species studied is discussed. The possible functions of these different molecules in retinal morphogenesis is also discussed.
Recommended Citation
Alles, Ajit Joseph, "The Distribution and Possible Significance of Glycoconjugates in Retinal Development" (1988). MUSC Theses and Dissertations. 27.
https://medica-musc.researchcommons.org/theses/27
Rights
All rights reserved. Copyright is held by the author.