Date of Award

2008

Document Type

Thesis

Department

Bioinformatics, Biostatistics, and Epidemiology

College

College of Graduate Studies

First Advisor

Daniel T. Lackland

Second Advisor

Barbara C. Tilley

Third Advisor

Perry V. Halushka

Fourth Advisor

Thomas C. Hulsey

Abstract

Arterial stiffness is considered both a risk factor and indicator of cardiovascular disease. The purpose of this study was to examine the associations of cardiovascular risk indicators of arterial compliance among 226 black and white individuals enrolled in an outpatient clinical setting. Data were collected by survey and examination with a computerized arterial pulse waveform analyzer. Arterial stiffness was estimated by indirect estimates of small artery and large artery compliance, as well as pulse pressure. After adjustments for age, race, and gender, logistic regression identified hypertension, end organ damage, and overweight as the strongest predictors for the three arterial stiffness indices. The results of this study identified similar factors associated with each of the different noninvasive measures of arterial stiffness.

Rights

All rights reserved. Copyright is held by the author.

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