Date of Award
3-16-2026
Embargo Period
4-1-2029
Document Type
Dissertation
Degree Name
Doctor of Health Administration
Department
Health Administration
College
College of Health Professions
First Advisor
Kit N. Simpson
Second Advisor
Sara Knox
Third Advisor
Todd Wandstrat
Abstract
This retrospective quantitative study investigated whether Medicare beneficiaries diagnosed with Alzheimer’s disease and related dementias (ADRD) in 2022 had prior diagnoses of Mild Cognitive Impairment (MCI) and examined healthcare costs in the five years before ADRD onset. Using a 5% national Medicare sample of beneficiaries aged 65 and older from 2017–2022, the study found that only 4.58% of 3,231 ADRD patients were diagnosed with MCI, highlighting underdiagnosis nationwide. Patients with MCI were generally younger, more likely to be male, African American, and dual-eligible for Medicare and Medicaid. Additionally, 43% of patients with an MCI diagnosis also had a behavioral dementia diagnosis. After adjusting for demographics and clinical factors, those with MCI incurred higher average annual healthcare costs ($28,256 versus $15,433). These findings emphasize the need for improved early detection strategies, including the use of biomarkers and artificial intelligence (AI)-based diagnostics. Recent U.S. policies support this goal, and proposed legislation, including the Alzheimer’s Screening and Prevention Act and the Accelerating Access to Dementia and Alzheimer’s Provider Training Act, aim to expand diagnostic access and strengthen primary care. Collectively, these developments underscore the urgency of earlier MCI identification to improve patient outcomes and reduce long-term healthcare costs.
Recommended Citation
Matheny, Helen, "Prior Mild Cognitive Impairment Among Medicare Beneficiaries With Alzheimer’s Disease: Neuropsychiatric Symptom Burden and Associated Healthcare Costs" (2026). MUSC Theses and Dissertations. 1105.
https://medica-musc.researchcommons.org/theses/1105
Rights
Copyright is held by the author. All rights reserved.