Simvastatin Suppresses LPS-Induced MMP-1 Expression in U937 Mononuclear Cells by Inhibiting Protein Isoprenylation-mediated ERK Activation

Keywords

geranylgeranyl pyrophosphate, lipopolysaccharides, matrix metalloproteinase 9, extracellular signal-regulated MAP kinases, simvastatin, MMP1 protein, matrix metalloproteinase 1, p38 mitogen-activated protein kinases, hydroxymethylglutaryl-CoA reductase inhibitors, matrix metalloproteinase 8, protein prenylation, polyisoprenyl phosphates, inflammation mediators

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