Document Type

Article

Embargo Period

1-1-2024

Publication Date

3-1-2005

Abstract

The DEAD-box RNA helicases are enzymes involved in many critical aspects of RNA metabolism within both eukaryotic and prokaryotic organisms. Several studies have shown that these proteins may have important functions in mediating microbial pathogenesis. A new study in this issue of the JCI identifies the first DEAD-box RNA helicase in the pathogenic fungus Cryptococcus neoformans and proposes novel roles for this family of proteins in the development and progression of cryptococcosis.

Journal

Journal of Clinical Investigation

DOI

doi: 10.1172/JCI200524508

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