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Born October 6, 1795, little is known about Henry Rutledge Frost’s early life. Like other founding faculty, he completed his medical studies at the University of Pennsylvania in 1816. He joined the Medical Society on August 1, 1817. Frost was elected to the professorship of Materia Medica, or pharmacology, in April 1824, a position he held throughout his teaching career. Frost served as the Medical College’s second dean for the 1828 to 1829 academic year, and again from 1843 to 1847 and 1850 to 1866.

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Frost’s Surgery, located on Broad Street (now Gaulart & Maliclet Fast and French restaurant) was a small, two-story masonry building that he renovated in 1835. According to the 1860 census, Frost’s slaveholdings totaled around $25,000.

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When classes were suspended following graduation ceremonies and the firing on Fort Sumter in April 1861, Frost served as South Carolina’s assistant surgeon for the 1st Artillery Regiment in the Confederate States Army and oversaw the hospital in Summerville. Frost died on April 7, 1866, having applied for a presidential pardon. He is buried at St. Philip’s Episcopal Church in Charleston.

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(Image Description: Lecture ticket for the Medical College of the State of South Carolina on Materia Medica. Waring Historical Library, Manuscript Collection, MSS 47.)